![]() Two days later, a real time-polymerase chain reaction (RT-PCR) of nasopharyngeal swab test confirmed that she had contracted Sars-CoV-2 infection. ![]() On November the 2 nd 2020, after having returned home from a hospital shift, she started feeling extremely tired and developed flu-like symptoms including cough, myalgia and loss of appetite. Our patient is a 47-year-old female nurse affected by chronic gastritis and gastroesophageal reflux disease for which she cyclically takes proton pump inhibitors. Hereby we report a case of atypical brachial plexitis in a patient admitted to our post-acute outpatient service “The Gemelli Against COVID-19 Post-Acute Care (GAC19-PAC)” for COVID-19 survivors at Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, Italy. However, little is known in relation to peripheral nerve injury in patients recovered from COVID-19. Long lasting fatigue, mild cognitive impairment and sleep disorders also seem to be frequent long term neurological manifestations after hospitalization due to COVID-19 and seem to be significantly related to the severity of respiratory symptoms, similarly to the acute phase. Neurological symptoms, such as headache or persistent loss of smell and taste, have also been documented in COVID-19 long-haulers. Neurological manifestations were more common in severe cases or in those with prolonged hospitalization. ![]() Furthermore, over the past two year, more complicated neurological manifestations, such as Guillain-Barré syndrome, have been reported in patients affected by COVID-19. CNS manifestations included dizziness, headache, impaired consciousness and seizures, vision impairment, while PNS included anosmia or dysgeusia, later identified as two cardinal symptoms of this diseases, but also neuropathic pain. In a retrospective study of 214 hospitalised patients with COVID-19, authors identified both central nervous system (CNS) and peripheral nervous system (PNS) manifestations. Whereas typical symptoms of COVID-19 involve mainly the respiratory system, neurological manifestations have been described since March 2020. The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (Sars-CoV-2), has crucially affected the life of everyone worldwide and significantly changed the course of history. A multidisciplinary approach to following-up COVID-19 survivors is strongly advised. The treatment of COVID-19 and its long-term consequences represents a relatively new challenge for clinicians and health care providers. A direct involvement of the virus remains uncertain, and the physiopathology is unclear. We presented a case of atypical Parsonage-Turner syndrome potentially triggered by Sars-CoV-2 infection, with symptoms and repercussion lasting after viral clearance. After referral to our post-acute outpatient service for COVID-19 long haulers, she was diagnosed with a unilateral, atypical, pure sensory brachial plexus neuritis potentially related to COVID-19, which occurred during the acute phase of a mild Sars-CoV-2 infection and persisted for months after resolution of the infection. We report the case of a 47-year-old female presenting with a unilateral chest pain radiating to the left arm lasting for more than two months after recovery from Sars-CoV-2 infection. Less is known in relation to peripheral nerve injury related to Sars-CoV-2 infection. Moreover, long lasting fatigue, mild cognitive impairment and sleep disorders appear to be frequent long term neurological manifestations after hospitalization due to COVID-19. Neurological manifestations of Sars-CoV-2 infection have been described since March 2020 and include both central and peripheral nervous system manifestations.
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